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ionispharma.com

https://ionispharma.com· First analyzed 22 May 2026· Updated 22 May 2026
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ionispharma.com
Desktop screenshot of ionispharma.com
Mobile screenshot of ionispharma.com
Mobile

Sponsored

Hosting Provider

Amazon Web Services (AWS)
aws.amazon.com

IP Address

75.2.103.146

Site Location

🇺🇸 United Statesvia ip

Server Location

🇺🇸 Seattle, United States

ASN

AS16509

Organization

AWS Global Accelerator (GLOBAL)

Server

Cloudflare

CDN

Cloudflare

WAF

Cloudflare

Nameservers

ns13.gcd-dns.com.ns14.gcd-dns.com.

Performance

100

Core Web Vitals

Weight

First Contentful Paint
415 ms10%
Speed Index
540 ms10%
Largest Contentful Paint
—25%
Total Blocking Time
0.0 ms30%
Cumulative Layout Shift
0.00025%
96 KB
76 requests

Image Optimization

Lazy LoadWebP
0–49
50–89
90–100

Architecture Stack

Monolithic
⚙️ SSR
Drupal

Technology Stack

4 Technologies Detected

CSS Frameworks

1
Tailwind CSS

Analytics

1
Google Analytics

Tag Managers

1
Google Tag Manager

CDN

1
Cloudflare

SEO Analysis

A84/100
24
4
0
Meta Tags15/15
Content11/12
Headings6/8
Technical22/25
E-E-A-T7/7
Images4/7
Links5/5
URL5/5
Social2/5
Freshness0/4
Mobile4/4
Indexability3/3
I
ionispharma.comionispharma.com

Innovating to Change the Course of Human Health | IONIS

Discover how we are enabling better futures for people living with serious disease through groundbreaking innovations. Learn about our mission here.

Title Length55 chars

Recommended: 50-60 chars (~333px / 580px)

Description Length148 chars

Recommended: 120-160 chars

Issues (0)

    4 issues found

    Upgrade to view details

    Crawlability

    Sitemap

    Type: standard

    32 URLs

    robots.txt

    52 rules

    Local SEO

    Local Search Readiness

    16/100
    Poor
    4 14

    This site doesn't appear to be a local business. Local SEO signals are optional for non-local websites.

    Sponsored

    AI & LLM Readiness

    D57/100
    Bot Access
    20/25
    Machine Read.
    12/25
    Schema Data
    8/25
    Citation
    17/25

    AI Bot Access

    14/14 accessible
    AI Search
    OAI-SearchBot
    PerplexityBot
    Claude-SearchBot
    Gemini-Deep-Research
    DuckAssistBot
    Training
    GPTBot
    ClaudeBot
    Google-Extended
    Meta-ExternalAgent
    Bytespiderinfo
    Amazonbot
    Applebot-Extended
    CCBotinfo
    Fetch
    ChatGPT-User

    Machine Readability

    llms.txt
    llms-full.txt
    Semantic HTML
    Heading Hierarchy
    navheader/footer
    Text ratio:11%
    Words:1,148
    Token eff.:Optimal
    Sections/1K:12.2
    Depth:2/5

    Structured Data

    3 JSON-LD
    Person×1.3(min)Organization×1.1WebSiteSearchAction
    sameAs entity links

    Citation Readiness

    Opening Summary37w
    Descriptive Headingsavg 8.7w
    Canonical URL
    Open Graph2/3
    Twitter Card0/3
    Language Tag
    Publish Date
    Author Info
    Lists
    Tables
    TL;DR / Summary
    About Page Link
    Recommendations (7)
    AI readiness recommendation preview...
    Upgrade to view recommendations

    Sponsored

    Accessibility

    WCAG 2.1 Compliance

    Evaluates how accessible your website is for users with disabilities, based on WCAG 2.1 guidelines. Checks images, forms, keyboard navigation, ARIA roles, and color contrast.
    B
    77/100
    11
    Passed
    2
    Critical
    2
    Warnings
    Images & Alt Text
    20/20
    Checks if images have descriptive alt text for screen readers and visually impaired users.
    Semantic Structure
    15/20
    Evaluates proper use of HTML5 semantic elements (header, nav, main, footer) and heading hierarchy.
    Forms & Inputs
    10/15
    Verifies form fields have labels, error messages are clear, and inputs are properly associated.
    Color & Contrast
    15/15
    Tests text-to-background color contrast ratios against WCAG AA/AAA minimum requirements.
    Keyboard & Focus
    13/15
    Ensures all interactive elements are reachable and operable via keyboard (tab, enter, escape).
    ARIA & Roles
    4/15
    Checks correct use of WAI-ARIA attributes (roles, states, properties) for assistive technologies.
    2 recommendations
    • •Accessibility recommendation preview...
    Upgrade to view recommendations

    Carbon Footprint

    SWDM v4 · Eco-Score

    Carbon emissions estimated using the Sustainable Web Design Model v4 (SWDM v4). Factors in data center, network, and device energy across new and returning visitors. Grade thresholds based on HTTP Archive percentiles.
    78/100
    A+
    10 mg
    CO₂e / view
    95.9 KB
    Page Weight
    95%
    Cleaner Than
    New Visitor
    11 mg
    vs
    Returning (cached)
    6 mg
    Annual (10K/mo)
    1.2 kg
    Emission Segments
    Data Center
    <0.001 g
    Network
    3 mg
    Device
    6 mg
    Resource Breakdown
    Images
    3.4 KB
    HTML
    10.6 KB
    Other
    81.9 KB
    Green Hosting Verified
    Amazon Web Services (AWS)
    Provider Match
    3 recommendations
    • •Carbon footprint recommendation preview...
    Upgrade to view recommendations
    D

    Security Score

    46%Poor
    Interactive

    HTTPS

    WAF

    71d

    Certificate Details

    Type

    Domain Validated (DV)

    Certificate Authority

    Google Trust Services

    Key Algorithm

    ECDSA (secp256r1) (256 bit)

    Signature

    ECDSA with SHA-256

    TLS Version

    TLSv1.3

    HTTP Protocol

    HTTP/2

    Valid From

    04.05.2026

    Valid Until

    02.08.2026

    OCSP Stapling

    Enabled

    Subject Alternative Names (2)

    ionis.com*.ionis.com

    SHA-256 Fingerprint

    0C:CF:F2:EE:67:A9:53:83:67:4A:3F:F7:93:99:B0:C5:0A:3C:27:E2...

    Top Recommendations

    Security recommendation preview

    Upgrade to view recommendations
    Upgrade to view header details

    HTTP Headers

    Developer Console

    age
    20790
    cache-control
    🟡 6 Hours(max-age=21600, public)
    cf-cache-status
    DYNAMIC
    cf-ray🇮🇹 Milan
    9ffe808b3a28ee51-MXP
    content-encoding
    📦 Gzip(gzip)
    content-language
    en
    Good Warning Issue

    Email Infrastructure

    Microsoft 365

    Score

    75

    SPF
    DKIM
    DMARC

    MX Records (1)

    ionispharma-com.mail.protection.outlook.com

    Domain Information

    ionispharma.com

    Domain Age
    10y 6m

    Created

    25.11.2015

    Expires

    25.11.2026

    Last Updated

    23.07.2025

    Registrar

    GoDaddy Corporate Domains, LLC

    DNSSEC
    Not Enabled

    Privacy & Compliance

    OneTrust

    Cookie Consent Banner
    OneTrust
    Privacy Policy
    Terms of Service

    GDPR Indicators

    Cookie consent banner detected
    CMP: OneTrust
    Privacy policy page linked
    Data Protection Officer mentioned

    Mobile Compatibility

    Viewport & Responsive Test

    Tests how well your website works on mobile devices. Checks viewport configuration, responsive layout, touch targets, font readability, and simulates rendering across different screen sizes.
    C
    66/100
    Mobile Friendly1 breakpoint
    Viewport Meta
    The viewport meta tag tells mobile browsers how to scale the page. Without it, mobile devices render at desktop width.
    Responsive Design
    Uses CSS media queries or flexible layouts to adapt content to different screen sizes automatically.
    Touch Icons
    Apple touch icons and favicons displayed when users add the site to their home screen on mobile devices.
    Readable Font Size
    Base font size should be at least 16px on mobile to ensure text is readable without zooming.
    Relative Units
    Using em, rem, %, or vw instead of fixed px values allows content to scale properly across screen sizes.
    No H-Scroll Risk
    No elements wider than the viewport that would cause horizontal scrolling on mobile devices.
    Tap Targets OK
    Interactive elements (buttons, links) are at least 48x48px with enough spacing to prevent accidental taps.
    No Fixed Widths
    No elements with fixed pixel widths that could overflow on smaller screens and break the layout.
    Viewport
    width=device-width, initial-scale=1.0
    1 recommendation
    • •Mobile compatibility recommendation preview...
    Upgrade to view recommendations

    Typography & Readability

    Gotham

    WCAG Partial
    79/100
    Readability
    /30
    26/30

    20px · LH 1.50

    Hierarchy
    /20
    18/20

    2.5x ratio · ✓ H1→H6

    WCAG
    /25
    17/25

    4.36:1 min contrast

    Performance
    /25
    18/25

    1 font · 6 req

    Heading Font

    Gotham

    Sans50px

    Body Font

    Gotham

    Sans20px

    Contrast Ratio

    4.36:1

    1 issue

    Reading Comfort

    ~36 CPL

    Narrow lines
    50px
    h1
    50px
    h2
    28px
    h3
    28px
    h4
    20px
    p

    ✅ Excellent readability: 20px body text is ideal for all devices.

    ✅ Optimal line spacing: 1.50 ratio (ideal range 1.4–1.6).

    ❌ Very complex text: Flesch score 20/100. Consider shorter sentences and simpler words.

    ⚠️ Partial contrast: 1 elements below WCAG AA threshold (min 4.4:1).

    ✅ Perfect heading hierarchy: Sequential h1→h2→h3 with single H1 — ideal for SEO & accessibility.

    ✅ Strong hierarchy: Headlines are 2.5x larger than body text.

    Buy on MyFontsFluid Type (rem)Flesch 20

    Color Palette

    10 unique colors
    4.08:1 AA Large Light
    #ebecee
    Background· 19.3%
    #787167
    Secondary· 5.8%
    #d60072
    Primary· 26.099999999999998%
    #d7dfe7
    Secondary· 14.8%
    #c78790
    Secondary· 8.4%
    #2a261f
    Secondary· 8.3%
    #e7d9c9
    Secondary· 3.5%
    #c00167
    Accent· 1.5%

    Business & Marketing Stack

    3 Tools Detected

    Advanced

    Behavior Analytics

    2
    Google Tag ManagerFree
    Google AnalyticsFree

    User behavior and product analytics

    Privacy & Cookies

    1
    OneTrustEnterprise

    Cookie consent and privacy compliance tools

    2

    Categories

    3

    Total Tools

    1

    Enterprise

    0

    Mid-Market

    Assessment: Well-developed marketing technology stack

    Sponsored

    Scripts & Styles

    22 Resources

    12
    Scripts
    10
    Styles
    1
    Async
    0
    Defer

    Top Script Sources

    local(9)googletagmanager.com(1)cdn.cookielaw.org(1)unpkg.com(1)

    Website Identity

    Ionis Pharmaceuticals, Inc

    Organization
    ionis.com/
    10 years old
    Location detected: 🇺🇸 United Statesvia ip
    GoDaddy Corporate Domains, LLC📧 Microsoft 365en

    Sponsored

    Last analyzed: 22 May 2026 at 20:17

    Historical Analysis & Change Tracking